Methylprednisolone Side Effects

Methylprednisolone side effects, like those of most other medications, are something you need to be aware of if your doctor feels you need to take this. They will usually goes over everything with you before prescribing any medication, especially a corticosteroid. They will determine, hopefully along with you, whether the benefits outweigh the risks.

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We've learned that methylprednisolone is sold under the brand names Solu-Medrol and Medrol. It is a synthetic glucocorticoid or steroid drug. Doctors prescribe it for their MS patients as an anti-inflammatory. It prevents substances that cause inflammation from being released into the body.

If you haven't already done so, click here to read the list of things you need to let your doctor know before taking methylprednisolone. There is an equally long list to tell your doctor about after you begin taking it. The following are methylprednisolone side effects.

Methylprednisolone side effects

  • Stomach upset
  • headache
  • dizziness
  • menstrual period changes
  • trouble sleeping
  • weight gain

Let your doctor know if any of these side effects won't go away or get worse. Hopefully you will be one of the ones that is not bothered by any of them. Unfortunately Cir had major problems with this particular steroid treatment. Especially with trouble sleeping, and headaches. He felt better otherwise, however, we decided next time to go with a different one - dexamethasone.

Rare, but serious

There are some rare, but very serious side effects that may happen, also. Call your doctor right away if you experience any of the following.

  • bone/joint pain
  • easy bruising/bleeding
  • black stools
  • vomit that looks like coffee grounds
  • severe stomach/abdominal pain
  • increased thirst/urination
  • fast/pounding/irregular heartbeat
  • shortness of breath
  • swelling of the ankles/feet
  • persistent weight gain
  • puffy face
  • unusual hair growth
  • thinning skin
  • slow wound healing
  • signs of infection (persistent fever/cough/sore throat, painful urination, eye pain/discharge)
  • muscle weakness/painmental/mood changes (mood swings, depression, agitation)
  • vision changes
  • seizures
  • unusual skin growths

Is it an allergic reaction?


A very serious allergic reaction to this drug is pretty rare, but you will need to get immediate medical attention if it does happen. How do you know if it's happening? Here are the symptoms that may indicate you are allergic to this medication – they may include:

  • rash
  • itching
  • swelling
  • severe dizziness
  • trouble breathing

You may notice other side effects not on this list. By all means let your doctor know anything that you feel is a result of taking this drug. Side effects like the five listed above are very rare, but they can happen. Be aware of how you feel. Know your body.

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