Each day he would take the shot in a different place, similar to how diabetics take insulin shots. Sometimes there was an injection site reaction.

He would put a little vitamin e ointment on the site - very lightly though. With subcutaneous (injections under the skin), you shouldn't rub the injection site immediately after taking the medicine. Sometimes Cir would wait until the next day to use the vitamin e.

Others have suggested using ice on the injection site before taking the injection. You put an ice pack or bag of peas on the site for a few minutes to numb the area. Use the alcohol wipe, then proceed with the shot or injection.

"I sense something here...

Cir always has an immediate reaction to the injection. A slight burning sensation that spreads slowly out from the site to the surrounding area. As the medicine spreads and goes throughout his body, the sensation goes away.

Occasionally a large red lump will appear after taking the injection. The next day the redness disappears. In its place is a hard lump. I notice this when the medicine goes in too quickly. If the syringe is pushed down slowly enough, I hardly ever notice a lump.

At this point (the next day), you can massage the lump and rub on vitamin e ointment if it's sore. Ice can also be used if there is still swelling.

Here is a helpful video with suggestions for dealing with copaxone injection site pain that I found.

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